Immunotherapy, a weapon against lung cancer - healthprevention.ch
 
Geneva:
+4122 840 33 34
 
Moscow:
+7(903)720 80 57

Immunotherapy, a weapon against lung cancer

Every year in Switzerland, more than three thousand people die from lung cancer, the most deadly of all cancers. Men are the most affected, but in industrialized countries their tumors are decreasing, as many of them have given up tobacco. On the other hand, the number of cases increased among women who started smoking a few decades ago. The cigarette is indeed the enemy No. 1 of the respiratory system.

Late detection
There are two main lung cancers that differ in their rate of progression, prognosis and treatment. The “non-small cell carcinoma”, which is the most frequent (80% of cases), and “small cell carcinoma”. that is the fastest, most aggressive and hardest to cure because, when detected, there are always a few tumor cells that are already circulating in the rest of the body. Whatever their type, tumors are mostly detected very late. This explains why the five-year survival rate is overall 20% for women and 15% for men –  whereas it can reach 60-70% if the tumor is detected at a very early stage.

The treatments used depend on the type of carcinoma and the stage reached by the cancer. If the tumor remains localized, it is eliminated by surgery or radiotherapy, sometimes accompanied by chemotherapy. This technique remains the only option in the most advanced stages, when there is metastasis.

In recent years, however, the therapeutic arsenal has expanded with the advent of drugs that target the tumor according to its biological profile. Some tumors, mainly non-small cell carcinomas, exhibit a genetic mutation that leads to the formation of an altered protein “inducing a crazy cell proliferation,”. The targeted treatments are therefore aimed at “repairing” this protein. Several drugs of this type are currently available in Switzerland. In people whose tumors have the target mutation, they are effective for one to three years. But then, the tumor finds the way to begin to proliferate and the cancer recidivates.

The greatest hope is, however, in immunotherapy, which aims to help our natural defenses to better fight cancer. Our immune system has weapons – white blood cells, called T-cells – capable of removing tumor cells. But if these are too numerous, it is overwhelmed by the task. Especially when the tumor is really malignant: when a T cell comes into contact with it, the tumor defends itself by disconnecting or by causing it to die. Immunotherapy therefore seeks to prevent it from doing so.

Treatments
Several immunotherapy drugs are already used in Switzerland. Reserved to patients – about one out of two – whose tumor has particular characteristics, they are then effective. Sixty percent of the people treated, most of whom had previously received chemotherapy, benefit from it, according to specialists. In 20% of cases, the tumor decreases in size and in others, it stops growing and stabilizes. “Surprisingly, tumors that were defending themselves the best way against the immune system and had the worst prognoses. are the most easily destroyed. In addition, unlike chemotherapy, immunotherapy does not attack healthy tissue and results in very few side effects.
Physicians also rely heavily on cell therapy. This technique, still experimental, consists of taking from the tumor of the patient T lymphocytes which are then “boosted” and cultivated in the laboratory and then reinjected into the blood of the patient. CHUV oncologists plan to launch a clinical trial in early autumn to test the efficacy of this method. It will be directed first to people with advanced melanoma and then, if it is conclusive, to those with lung cancer.

Comments
Articles
Patient registration form
Topics
Examination Incorpore
nutrition
oncology
prevention
cancer
dermatology
age management
Anti-aging
detoxification
skin
heavy metal
diagnosis
cardiology
immunology
stem cells
weight management
oncology treatment
liver detox
DNA
Genetics
allergy
pain
Fertility
Examination partner centres
gastroenterology
covid19
weight loss
cosmetology
liver
infertility
chelation
Sleep
gynecology
urology
radiology
neurology
check-up
skincare
pregnancy
Hepatitis C
rehabilitation
headache
breast cancer
candida
arsenic
anti-aging
obstetrics
joints
immune system
Дерматология
heart MRI
immunotherapy
NAD+
Blood pressure
mesotherapy
probiotics
Apnea
tinnitus
ulcer
abdominal pain
pancreas
research
sexuality
beau-rivage
nutrigenomics
migraine
menopause
telomere
gastritis
flu vaccine
regeneration
PRP
andropause
light therapy
excimer laser
psoriasis
hyaluronic acid
sugar
obstertics
rhesus factor
Allergology
preventiion
gastroscopy
brain surgery awake
mastectomy
digestion
mammography
cellmen
cellcosmet
herniated disc
flu
magnesium
R-loops
Omega-3
shoulder
hand
intestinal flora
depression
iron
second opinion
food intolerances
reflexology
food
vitamin b12
mercury
water
erectile dysfunction
back pain
hip
knee
beauty
exercise
sports
cholesterol
stress
vitamin K
narcosis
diabetes
cellulite
acnea
migraines
chronic headaches
diet
oncoloy
reconstruction
blood test
endometriosis
acne
LED therapy
biopsy
liquid biopsy
oral checkup
propofole
dermatitis
hormones
general surgery
nephrology
kidney
ophthalmology
plastic surgery
lungs
pneumology
proctology
pomegranate
rheumatology
orthopedics
colonoscopy
endocrinology
Treatment programs